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Different Modes of Cell‐killing Action between DNA Topoisomerase I and II Inhibitors Revealed by Kinetic Analysis

We compared the modes of cell‐killing by DNA topoisomerase I and II inhibitors. The effects of camptothecin (CPT), KT‐6528 and UCE6 upon colony formation by inhibiting DNA topoisomerase I, and of etoposide (VF‐16), teniposide, amsacrine and UCT4‐A as inhibitors of DNA topoisomerase II were analyzed...

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Detalhes bibliográficos
Publicado no:Jpn J Cancer Res
Main Authors: Inaba, Makoto, Mitsuhashi, Junko, Kawada, Shouzou, Nakano, Hirofumi
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 1994
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5919418/
https://ncbi.nlm.nih.gov/pubmed/8144400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1994.tb02081.x
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