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Enhancement of T Cell Receptor Signaling of Tumor‐infiltrating Lymphocytes by Retrovirally Mediated fyn Gene Transduction

We conducted retrovirally mediated transduction of fyn gene into tumor‐infiltrating lymphocytes (TILs) in an attempt to augment T cell receptor‐CD3 complex signal transduction, using TILs obtained from six patients with epithelial ovarian cancer. The expression of the transduced gene was more than f...

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Detalhes bibliográficos
Publicado no:Jpn J Cancer Res
Main Authors: Fujita, Kazuyuki, Ikarashi, Hirokazu, Takakuwa, Koichi, Kodama, Shoji, Akagi, Tsuyoshi, Yamamoto, Tadashi, Tanaka, Kenichi
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 1994
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5919375/
https://ncbi.nlm.nih.gov/pubmed/7829390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1994.tb02909.x
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