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H‐2(Z) Homozygous New Zealand Mice as a Model for B‐Cell Chronic Lymphocytic Leukemia: Elevated bcl‐2 Expression in CD5 B Cells at Premalignant and Malignant Stages
In New Zealand mice, the major histocompatibility complex (MHC) controls the development of both autoimmune disease and B cell chronic lymphocytic leukemia (B‐CLL). While H‐2(d)/H‐2(z) heterozygosity acts as one major predisposing genetic element for autoimmune disease, H‐2(z)/H‐2(z) homozygosity ac...
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| Publicado no: | Jpn J Cancer Res |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Publishing Ltd
1993
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5919115/ https://ncbi.nlm.nih.gov/pubmed/7507474 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1993.tb02834.x |
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