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Precursor B cells for autoantibody production in genomically Fas-intact autoimmune disease are not subject to Fas-mediated immune elimination

The Fas/Fas ligand (FasL) system participates in regulation of the immune system through the apoptotic process. However, the extent to which abnormalities in this system are involved in the loss of self-tolerance and development of autoimmune disease not associated with Fas/FasL mutations remains un...

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Detalhes bibliográficos
Main Authors: Hirose, Sachiko, Yan, Kwangseok, Abe, Masaaki, Jiang, Yi, Hamano, Yoshitomo, Tsurui, Hiromichi, Shirai, Toshikazu
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences of the USA 1997
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC23161/
https://ncbi.nlm.nih.gov/pubmed/9256475
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