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A molecular dynamics study of adenylyl cyclase: The impact of ATP and G-protein binding

Adenylyl cyclases (ACs) catalyze the biosynthesis of cyclic adenosine monophosphate (cAMP) from adenosine triphosphate (ATP) and play an important role in many signal transduction pathways. The enzymatic activity of ACs is carefully controlled by a variety of molecules, including G-protein subunits...

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Publicat a:PLoS One
Autors principals: Frezza, Elisa, Martin, Juliette, Lavery, Richard
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2018
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5918993/
https://ncbi.nlm.nih.gov/pubmed/29694437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0196207
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