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A molecular dynamics study of adenylyl cyclase: The impact of ATP and G-protein binding

Adenylyl cyclases (ACs) catalyze the biosynthesis of cyclic adenosine monophosphate (cAMP) from adenosine triphosphate (ATP) and play an important role in many signal transduction pathways. The enzymatic activity of ACs is carefully controlled by a variety of molecules, including G-protein subunits...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Frezza, Elisa, Martin, Juliette, Lavery, Richard
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5918993/
https://ncbi.nlm.nih.gov/pubmed/29694437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0196207
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