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High Incidence of p53 Gene Mutation in Human Ovarian Cancer and Its Association with Nuclear Accumulation of p53 Protein and Tumor DNA Aneuploidy

Using the poylmerase chain reaction and single‐strand conformation polymorphism analysis, p53 gene mutations were examined in 24 cases of ovarian tumor including 14 ovarian carcinomas and 2 borderline cases of common epithelial type, 7 germ cell tumors, and one stromal tumor. Abnormal bands indicati...

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Detalhes bibliográficos
Publicado no:Jpn J Cancer Res
Main Authors: Kihana, Toshimasa, Tsuda, Hitoshi, Teshima, Shinichi, Okada, Shuichi, Matsuura, Shumpei, Hirohashi, Setsuo
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 1992
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5918982/
https://ncbi.nlm.nih.gov/pubmed/1429209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1992.tb02010.x
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