High Incidence of p53 Gene Mutation in Human Ovarian Cancer and Its Association with Nuclear Accumulation of p53 Protein and Tumor DNA Aneuploidy

Using the poylmerase chain reaction and single‐strand conformation polymorphism analysis, p53 gene mutations were examined in 24 cases of ovarian tumor including 14 ovarian carcinomas and 2 borderline cases of common epithelial type, 7 germ cell tumors, and one stromal tumor. Abnormal bands indicati...

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Bibliographic Details
Published in:Jpn J Cancer Res
Main Authors: Kihana, Toshimasa, Tsuda, Hitoshi, Teshima, Shinichi, Okada, Shuichi, Matsuura, Shumpei, Hirohashi, Setsuo
Format: Artigo
Language:Inglês
Published: Blackwell Publishing Ltd 1992
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5918982/
https://ncbi.nlm.nih.gov/pubmed/1429209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1992.tb02010.x
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