High Incidence of p53 Gene Mutation in Human Ovarian Cancer and Its Association with Nuclear Accumulation of p53 Protein and Tumor DNA Aneuploidy

Using the poylmerase chain reaction and single‐strand conformation polymorphism analysis, p53 gene mutations were examined in 24 cases of ovarian tumor including 14 ovarian carcinomas and 2 borderline cases of common epithelial type, 7 germ cell tumors, and one stromal tumor. Abnormal bands indicati...

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Veröffentlicht in:Jpn J Cancer Res
Hauptverfasser: Kihana, Toshimasa, Tsuda, Hitoshi, Teshima, Shinichi, Okada, Shuichi, Matsuura, Shumpei, Hirohashi, Setsuo
Format: Artigo
Sprache:Inglês
Veröffentlicht: Blackwell Publishing Ltd 1992
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5918982/
https://ncbi.nlm.nih.gov/pubmed/1429209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1992.tb02010.x
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