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The Number of Platinum Atoms Binding to DNA, RNA and Protein Molecules of HeLa Cells Treated with Cisplatin at Its Mean Lethal Concentration

HeLa S‐3 cells were treated with (195m)Pt‐radiolabeled cis‐diamminedichloroplatinum(II) (CDDP) under various conditions, and the relationship between lethal effect and the number of Pt atoms binding to DNA, RNA and proteins was examined. The mean lethal concentrations for the cells treated with CDDP...

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Detalhes bibliográficos
Publicado no:Jpn J Cancer Res
Main Authors: Akaboshi, Mitsuhiko, Kawai, Kenichi, Maki, Hirotoshi, Akuta, Keizo, Ujeno, Yowri, Miyahara, Tokiharu
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 1992
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5918865/
https://ncbi.nlm.nih.gov/pubmed/1618702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1992.tb01959.x
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