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The Number of Platinum Atoms Binding to DNA, RNA and Protein Molecules of HeLa Cells Treated with Cisplatin at Its Mean Lethal Concentration

HeLa S‐3 cells were treated with (195m)Pt‐radiolabeled cis‐diamminedichloroplatinum(II) (CDDP) under various conditions, and the relationship between lethal effect and the number of Pt atoms binding to DNA, RNA and proteins was examined. The mean lethal concentrations for the cells treated with CDDP...

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Bibliografiset tiedot
Julkaisussa:Jpn J Cancer Res
Päätekijät: Akaboshi, Mitsuhiko, Kawai, Kenichi, Maki, Hirotoshi, Akuta, Keizo, Ujeno, Yowri, Miyahara, Tokiharu
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Blackwell Publishing Ltd 1992
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5918865/
https://ncbi.nlm.nih.gov/pubmed/1618702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1992.tb01959.x
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