In vitro Progression‐associated c‐H‐ras Activation in Neoplastic Hepatocyte Lines Established from SV40‐T Antigen Gene‐harboring Transgenic Mice

In order to investigate the molecular mechanisms of multistep hepatocarcinogenesis in SV40‐T antigen gene‐harboring transgenic mice, 9 hepatocellular carcinoma (HCC) lines and 10 “preneoplastic” hepatocyte lines were established from the animals and their biological and molecular changes during cult...

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Bibliographic Details
Published in:Jpn J Cancer Res
Main Authors: Li, Hong, Liu, Jia, Nomura, Kimie, Lee, Gang‐Hong, Hino, Okio, Ohtake, Keiko, Aizawa, Shinichi, Kitagawa, Tomoyuki
Format: Artigo
Language:Inglês
Published: Blackwell Publishing Ltd 1991
Subjects:
Rapid Communication
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5918201/
https://ncbi.nlm.nih.gov/pubmed/1900265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1991.tb01736.x
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