Transgenic Mice Harboring SV40 T-Antigen Genes Develop Characteristic Brain Tumors

A high percentage of transgenic mice developing from eggs microinjected with plasmids containing the SV40 early region genes and a metallothionein fusion gene develop tumors within the choroid plexus. A line of mice has been established in which nearly every affected animal succumbs to this brain tu...

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發表在:Cell
Main Authors: Brinster, Ralph L., Chen, Howard Y., Messing, Albee, van Dyke, Terry, Levine, Arnold J., Palmiter, Richard D.
格式: Artigo
語言:Inglês
出版: 1984
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4889224/
https://ncbi.nlm.nih.gov/pubmed/6327063
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