A model for primitive neuroectodermal tumors in transgenic neural transplants harboring the SV40 large T antigen.

Using retrovirus-mediated transfer of the SV40 virus large T antigen into neural transplants, we have observed a high incidence of primitive neuroectodermal tumors (PNET). These neoplasms developed in 8 of 14 (57%) neural grafts after latency periods of 176 to 311 days. Histopathologically, the tumo...

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Detalles Bibliográficos
Main Authors: Eibl, R. H., Kleihues, P., Jat, P. S., Wiestler, O. D.
Formato: Artigo
Idioma:Inglês
Publicado: 1994
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1887088/
https://ncbi.nlm.nih.gov/pubmed/8129041
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