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Hypomyelinating peripheral neuropathies and schwannomas in transgenic mice expressing SV40 T-antigen
We have prepared transgenic mice carrying a temperature-sensitive mutant of the SV40 oncogene (tsA-1609) under the control of 5′ flanking sequences from the Schwann cell-specific P0 gene. Four of six founder mice showed moderate to severe hypomyelination in peripheral nerves of tail biopsies, with o...
Shranjeno v:
| izdano v: | J Neurosci |
|---|---|
| Main Authors: | , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Society for Neuroscience
1994
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6576935/ https://ncbi.nlm.nih.gov/pubmed/7515952 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.14-06-03533.1994 |
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