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Antitumor Activity and Pharmacology of 1‐β‐D‐Arabinofuranosylcytosine‐5′‐stearylphosphate: An Orally Active Derivative of 1‐β‐D‐Arabinofuranosylcytosine

The antitumor activity of l‐β‐D‐arabinofuranosylcytosine‐5′‐alkylphosphates (CnPCAs) against L1210 leukemia in mice after oral administration was demonstrated. The optimum length of the alkyl group on the phosphate moiety of CnPCA for exhibiting a high antitumor activity was found to be between tetr...

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Dettagli Bibliografici
Pubblicato in:Jpn J Cancer Res
Autori principali: Kodama, Kenjiro, Morozumi, Manami, Saitoh, Ken‐ichi, Kuninaka, Akira, Yoshino, Hiroshi, Saneyoshi, Mineo
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Publishing Ltd 1989
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5917809/
https://ncbi.nlm.nih.gov/pubmed/2507491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1989.tb01696.x
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