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Antitumor Activity and Pharmacology of 1‐β‐D‐Arabinofuranosylcytosine‐5′‐stearylphosphate: An Orally Active Derivative of 1‐β‐D‐Arabinofuranosylcytosine

The antitumor activity of l‐β‐D‐arabinofuranosylcytosine‐5′‐alkylphosphates (CnPCAs) against L1210 leukemia in mice after oral administration was demonstrated. The optimum length of the alkyl group on the phosphate moiety of CnPCA for exhibiting a high antitumor activity was found to be between tetr...

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Detalles Bibliográficos
Publicado en:Jpn J Cancer Res
Main Authors: Kodama, Kenjiro, Morozumi, Manami, Saitoh, Ken‐ichi, Kuninaka, Akira, Yoshino, Hiroshi, Saneyoshi, Mineo
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Publishing Ltd 1989
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5917809/
https://ncbi.nlm.nih.gov/pubmed/2507491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1989.tb01696.x
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