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Antitumor Activity and Pharmacology of 1‐β‐D‐Arabinofuranosylcytosine‐5′‐stearylphosphate: An Orally Active Derivative of 1‐β‐D‐Arabinofuranosylcytosine

The antitumor activity of l‐β‐D‐arabinofuranosylcytosine‐5′‐alkylphosphates (CnPCAs) against L1210 leukemia in mice after oral administration was demonstrated. The optimum length of the alkyl group on the phosphate moiety of CnPCA for exhibiting a high antitumor activity was found to be between tetr...

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Bibliografische gegevens
Gepubliceerd in:Jpn J Cancer Res
Hoofdauteurs: Kodama, Kenjiro, Morozumi, Manami, Saitoh, Ken‐ichi, Kuninaka, Akira, Yoshino, Hiroshi, Saneyoshi, Mineo
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Blackwell Publishing Ltd 1989
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5917809/
https://ncbi.nlm.nih.gov/pubmed/2507491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1989.tb01696.x
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