Salidroside Promotes the Pathological α-Synuclein Clearance Through Ubiquitin-Proteasome System in SH-SY5Y Cells

Parkinson’s disease (PD) is characterized by the loss of dopaminergic (DA) neurons in the substantia nigra pars compacta (SNc) and the presence of Lewy bodies (LBs) in the surviving SNc neurons. LBs formation is caused by the accumulation of α-synuclein (α-syn) or phosphorylated α-syn at serine-129...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Li, Tao, Feng, Yang, Yang, Ruixin, Wu, Leitao, Li, Ruru, Huang, Lu, Yang, Qian, Chen, Jianzong
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5917065/
https://ncbi.nlm.nih.gov/pubmed/29725300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.00377
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