Salidroside Promotes the Pathological α-Synuclein Clearance Through Ubiquitin-Proteasome System in SH-SY5Y Cells

Parkinson’s disease (PD) is characterized by the loss of dopaminergic (DA) neurons in the substantia nigra pars compacta (SNc) and the presence of Lewy bodies (LBs) in the surviving SNc neurons. LBs formation is caused by the accumulation of α-synuclein (α-syn) or phosphorylated α-syn at serine-129...

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Опубликовано в: :Front Pharmacol
Главные авторы: Li, Tao, Feng, Yang, Yang, Ruixin, Wu, Leitao, Li, Ruru, Huang, Lu, Yang, Qian, Chen, Jianzong
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2018
Предметы:
Pharmacology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5917065/
https://ncbi.nlm.nih.gov/pubmed/29725300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.00377
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