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Crosstalk between the proteasome system and autophagy in the clearance of α-synuclein

AIM: A growing body of evidence suggests that α-synuclein accumulation may play an important role in the pathogenesis of Parkinson's disease. The aim of this study was to investigate the roles of the proteasome and autophagy pathways in the clearance of wild-type and mutant α-synuclein in PC12...

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Detalhes bibliográficos
Main Authors: Yang, Fang, Yang, Ya-ping, Mao, Cheng-jie, Liu, Ling, Zheng, Hui-fen, Hu, Li-fang, Liu, Chun-feng
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4002879/
https://ncbi.nlm.nih.gov/pubmed/23603979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2013.29
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