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Differential Hyperphosphorylation of Tau-S199, -T231 and -S396 in Organotypic Brain Slices of Alzheimer Mice. A Model to Study Early Tau Hyperphosphorylation Using Okadaic Acid

Alzheimer’s disease (AD) is a progressive neurodegenerative disorder of the brain, characterized by extracellular aggregation of beta-amyloid (Aβ) and hyperphosphorylation of tau causing intraneuronal neurofibrillary tangles (NFTs). There is urgent need to study the interactions between Aβ and tau,...

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Dades bibliogràfiques
Publicat a:Front Aging Neurosci
Autors principals: Foidl, Bettina M., Humpel, Christian
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5917035/
https://ncbi.nlm.nih.gov/pubmed/29725295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2018.00113
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