Can mouse models mimic sporadic Alzheimer’s disease?

Alzheimer’s disease (AD) is a progressive neurodegenerative disorder and the most common form of dementia worldwide. As age is the main risk factor, > 97% of all AD cases are of sporadic origin, potentiated by various risk factors associated with life style and starting at an age > 60 years. O...

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Detalhes bibliográficos
Main Authors: Bettina M Foidl, Christian Humpel
Formato: Artigo
Idioma:Inglês
Publicado em: Wolters Kluwer Medknow Publications 2020-01-01
Colecção:Neural Regeneration Research
Assuntos:
Alzheimer’s disease; beta-amyloid; cerebral amyloid angiopathy; cognitive impairment; sporadic and genetic mouse models; tau; vascular risk factors
Acesso em linha:http://www.nrronline.org/article.asp?issn=1673-5374;year=2020;volume=15;issue=3;spage=401;epage=406;aulast=Foidl
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