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Dacarbazine depletes the ovarian reserve in mice and depletion is enhanced with age
Dacarbazine is commonly administered for the treatment of cancers prevalent in reproductive age females. However, investigations of off-target effects of dacarbazine on the ovary are limited. We assessed the impact of dacarbazine on the ovarian reserve of primordial follicles, essential for fertilit...
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| 出版年: | Sci Rep |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group UK
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5917018/ https://ncbi.nlm.nih.gov/pubmed/29695822 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-24960-5 |
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