The ovarian reserve is depleted during puberty in a hormonally driven process dependent on the pro-apoptotic protein BMF

In females, germ cells are maintained in ovarian structures called primordial follicles. The number of primordial follicles in the ovarian reserve is a critical determinant of the length of the fertile lifespan. Despite this significance, knowledge of the precise physiological mechanisms that regula...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell Death Dis
Prif Awduron: Liew, Seng H, Nguyen, Quynh-Nhu, Strasser, Andreas, Findlay, Jock K, Hutt, Karla J
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2017
Pynciau:
Original Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5596551/
https://ncbi.nlm.nih.gov/pubmed/28771225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.361
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