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The ovarian reserve is depleted during puberty in a hormonally driven process dependent on the pro-apoptotic protein BMF
In females, germ cells are maintained in ovarian structures called primordial follicles. The number of primordial follicles in the ovarian reserve is a critical determinant of the length of the fertile lifespan. Despite this significance, knowledge of the precise physiological mechanisms that regula...
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Publicado no: | Cell Death Dis |
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Main Authors: | , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5596551/ https://ncbi.nlm.nih.gov/pubmed/28771225 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.361 |
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