Ibrutinib inhibition of ERBB4 reduces cell growth in a WNT5A-dependent manner

Alterations in ERBB family members have been associated with many tumor malignancies. EGFR and ERBB2 have been extensively explored in clinical oncology and several drugs currently target them therapeutically. However, the significance of ERBB4 as a potential therapeutic target remains mostly unexpl...

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Gepubliceerd in:Oncogene
Hoofdauteurs: Rauf, Femina, Festa, Fernanda, Park, Jin G., Magee, Mitchell, Eaton, Seron, Rinaldi, Capria, Betanzos, Carlos Morales, Gonzalez-Malerva, Laura, LaBaer, Joshua
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2018
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5916919/
https://ncbi.nlm.nih.gov/pubmed/29398709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-017-0079-x
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