Isolation and characterization of a monoclonal antibody containing an extra heavy-light chain Fab arm

Isolation and characterization of monoclonal antibody (mAb) variants to understand the impact of their structure on function is a typical activity during early-stage candidate selection that contributes to derisking clinical development. In particular, efforts are devoted to characterizing oligomeri...

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Bibliographische Detailangaben
Veröffentlicht in:MAbs
Hauptverfasser: Boyd, Dan, Ebrahimi, Arpa, Ronan, Sarah, Mickus, Brian, Schenauer, Matthew, Wang, Jenny, Brown, Darren, Ambrogelly, Alexandre
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2018
Schlagworte:
Brief Report
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5916558/
https://ncbi.nlm.nih.gov/pubmed/29537936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2018.1438795
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