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Benchmarking lithium amide versus amine bonding by charge density and energy decomposition analysis arguments

Lithium amides are versatile C–H metallation reagents with vast industrial demand because of their high basicity combined with their weak nucleophilicity, and they are applied in kilotons worldwide annually. The nuclearity of lithium amides, however, modifies and steers reactivity, region- and stere...

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Detalhes bibliográficos
Publicado no:Chem Sci
Main Authors: Engelhardt, Felix, Maaß, Christian, Andrada, Diego M., Herbst-Irmer, Regine, Stalke, Dietmar
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5916014/
https://ncbi.nlm.nih.gov/pubmed/29732094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7sc05368a
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