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Novel aspects of the assembly and activation of inflammasomes with focus on the NLRC4 inflammasome
Inflammasomes are multiprotein structures that activate caspase-1, support secretion of pro-inflammatory cytokines, IL-1β and IL-18, and also induce inflammatory programmed cell death, termed pyoptosis. Inflammasomes are activated in response to the detection of endogenous and microbially derived da...
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| Publicado no: | Int Immunol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5915955/ https://ncbi.nlm.nih.gov/pubmed/29617808 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/intimm/dxy009 |
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