Wordt geladen...
New chemical tools for probing activity and inhibition of the NAD(+)-dependent lysine deacylase sirtuin 2
Sirtuins are NAD(+)-dependent protein deacylases capable of cleaving off acetyl as well as other acyl groups from the ɛ-amino group of lysines in histones and other substrate proteins. They have been reported as promising drug targets, and thus modulators of their activity are needed as molecular to...
Bewaard in:
| Gepubliceerd in: | Philos Trans R Soc Lond B Biol Sci |
|---|---|
| Hoofdauteurs: | , , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
The Royal Society
2018
|
| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5915722/ https://ncbi.nlm.nih.gov/pubmed/29685963 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2017.0083 |
| Tags: |
Voeg label toe
Geen labels, Wees de eerste die dit record labelt!
|