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Allelic interaction effects of DNA damage and repair genes on the predisposition to age-related cataract

PURPOSE: Age-related cataract (ARC) is a leading cause of visual impairment and blindness worldwide. DNA damage and malfunction of DNA repair are believed to contribute to the pathogenesis of ARC. Aside from increasing age, the risk factors for ARC appear to be rather complex, and one or more gene v...

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Detalles Bibliográficos
Publicado en:PLoS One
Main Authors: Yang, Mei, Zhang, Junfang, Su, Shu, Qin, Bai, Kang, Lihua, Zhu, Rongrong, Guan, Huaijin
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5915686/
https://ncbi.nlm.nih.gov/pubmed/29689049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0184478
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