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Multivalent recruitment of human Argonaute by GW182
In miRNA mediated gene silencing the physical interaction between human Argonaute (hAgo) and GW182 (hGW182) is essential for facilitating the downstream silencing of the targeted mRNA. GW182 can interact with hAgo via three of the GW/WG repeats in its Argonaute-binding domain: motif-1, motif-2 and t...
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| I publikationen: | Mol Cell |
|---|---|
| Huvudupphovsmän: | , , , , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
2017
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5915679/ https://ncbi.nlm.nih.gov/pubmed/28781232 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2017.07.007 |
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