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Structural features of Argonaute–GW182 protein interactions

MicroRNAs (miRNAs) guide Argonaute (Ago) proteins to target mRNAs, leading to gene silencing. However, Ago proteins are not the actual mediators of gene silencing but interact with a member of the GW182 protein family (also known as GW proteins), which coordinates all downstream steps in gene silenc...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Pfaff, Janina, Hennig, Janosch, Herzog, Franz, Aebersold, Ruedi, Sattler, Michael, Niessing, Dierk, Meister, Gunter
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3791723/
https://ncbi.nlm.nih.gov/pubmed/24043833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1308510110
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