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Argonaute MID domain takes centre stage

Two recent papers, one in EMBO reports and one in Nature give us the first eukaryotic structures of Argonaute MID domains; providing a structural basis for the 5′-nucleotide recognition of the guide strand and a possible explanation for the allosteric regulation of RNA binding.

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Autori principali: Faehnle, Christopher R, Joshua-Tor, Leemor
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2920440/
https://ncbi.nlm.nih.gov/pubmed/20634804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2010.110
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