Elf3 Contributes to Cartilage Degradation in vivo in a Surgical Model of Post-Traumatic Osteoarthritis

The E-74 like factor 3 (ELF3) is a transcription factor induced by inflammatory factors in various cell types, including chondrocytes. ELF3 levels are elevated in human cartilage from patients with osteoarthritis (OA), and ELF3 contributes to the IL-1β-induced expression of genes encoding Mmp13, Nos...

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Publicat a:Sci Rep
Autors principals: Wondimu, Elisabeth B., Culley, Kirsty L., Quinn, Justin, Chang, Jun, Dragomir, Cecilia L., Plumb, Darren A., Goldring, Mary B., Otero, Miguel
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5915581/
https://ncbi.nlm.nih.gov/pubmed/29691435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-24695-3
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