Effects of pre-existing orthopoxvirus-specific immunity on the performance of Modified Vaccinia virus Ankara-based influenza vaccines

The replication-deficient orthopoxvirus modified vaccinia virus Ankara (MVA) is a promising vaccine vector against various pathogens and has an excellent safety record. However, pre-existing vector-specific immunity is frequently suggested to be a drawback of MVA-based vaccines. To address this issu...

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Publicado no:Sci Rep
Main Authors: Altenburg, Arwen F., van Trierum, Stella E., de Bruin, Erwin, de Meulder, Dennis, van de Sandt, Carolien E., van der Klis, Fiona R. M., Fouchier, Ron A. M., Koopmans, Marion P. G., Rimmelzwaan, Guus F., de Vries, Rory D.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5915537/
https://ncbi.nlm.nih.gov/pubmed/29692427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-24820-2
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