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Modified Vaccinia Virus Ankara Preferentially Targets Antigen Presenting Cells In Vitro, Ex Vivo and In Vivo

Modified Vaccinia virus Ankara (MVA) is a promising vaccine vector with an excellent safety profile. However, despite extensive pre-clinical and clinical testing, surprisingly little is known about the cellular tropism of MVA, especially in relevant animal species. Here, we performed in vitro, ex vi...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Altenburg, Arwen F., van de Sandt, Carolien E., Li, Bobby W. S., MacLoughlin, Ronan J., Fouchier, Ron A. M., van Amerongen, Geert, Volz, Asisa, Hendriks, Rudi W., de Swart, Rik L., Sutter, Gerd, Rimmelzwaan, Guus F., de Vries, Rory D.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5561217/
https://ncbi.nlm.nih.gov/pubmed/28819261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-08719-y
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