Induction of Cross-Clade Antibody and T-Cell Responses by a Modified Vaccinia Virus Ankara–Based Influenza A(H5N1) Vaccine in a Randomized Phase 1/2a Clinical Trial

BACKGROUND: High-pathogenicity avian influenza viruses continue to circulate in poultry and wild birds and occasionally infect humans, sometimes with fatal outcomes. Development of vaccines is a priority to prepare for potential pandemics but is complicated by antigenic variation of the surface glyc...

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Dettagli Bibliografici
Pubblicato in:J Infect Dis
Autori principali: de Vries, Rory D, Altenburg, Arwen F, Nieuwkoop, Nella J, de Bruin, Erwin, van Trierum, Stella E, Pronk, Mark R, Lamers, Mart M, Richard, Mathilde, Nieuwenhuijse, David F, Koopmans, Marion P G, Kreijtz, Joost H C M, Fouchier, Ron A M, Osterhaus, Albert D M E, Sutter, Gerd, Rimmelzwaan, Guus F
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2018
Soggetti:
Major Articles and Brief Reports
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6047453/
https://ncbi.nlm.nih.gov/pubmed/29912453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiy214
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