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Deoxyribonucleotide Triphosphate Metabolism in Cancer and Metabolic Disease
The maintenance of a healthy deoxyribonucleotide triphosphate (dNTP) pool is critical for the proper replication and repair of both nuclear and mitochondrial DNA. Temporal, spatial, and ratio imbalances of the four dNTPs have been shown to have a mutagenic and cytotoxic effect. It is, therefore, ess...
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| Publié dans: | Front Endocrinol (Lausanne) |
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| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Frontiers Media S.A.
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5915462/ https://ncbi.nlm.nih.gov/pubmed/29720963 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2018.00177 |
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