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Deoxyribonucleotide Triphosphate Metabolism in Cancer and Metabolic Disease

The maintenance of a healthy deoxyribonucleotide triphosphate (dNTP) pool is critical for the proper replication and repair of both nuclear and mitochondrial DNA. Temporal, spatial, and ratio imbalances of the four dNTPs have been shown to have a mutagenic and cytotoxic effect. It is, therefore, ess...

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Bibliografiske detaljer
Udgivet i:Front Endocrinol (Lausanne)
Main Authors: Buj, Raquel, Aird, Katherine M.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5915462/
https://ncbi.nlm.nih.gov/pubmed/29720963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2018.00177
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