Simultaneous isotope dilution quantification and metabolic tracing of deoxyribonucleotides by liquid chromatography high resolution mass spectrometry

Quantification of cellular deoxyribonucleoside mono- (dNMP), di- (dNDP), triphosphates (dNTPs) and related nucleoside metabolites are difficult due to their physiochemical properties and widely varying abundance. Involvement of dNTP metabolism in cellular processes including senescence and pathophys...

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Publicado no:Anal Biochem
Main Authors: Kuskovsky, Rostislav, Buj, Raquel, Xu, Peining, Hofbauer, Samuel, Doan, Mary T, Jiang, Helen, Bostwick, Anna, Mesaros, Clementina, Aird, Katherine M., Snyder, Nathaniel W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7359880/
https://ncbi.nlm.nih.gov/pubmed/30605633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2018.12.023
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