The Hippo Signaling Transducer TAZ Regulates Mammary Gland Morphogenesis and Carcinogen-induced Mammary Tumorigenesis

Hippo signaling pathway is an evolutionarily conserved pathway that controls organ size by regulating cell proliferation, apoptosis and stem cell self-renewal. TAZ (transcriptional coactivator with the PDZ-binding motif) is a key downstream effector of the mammalian Hippo pathway. Here, using a tran...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Denson, Kayla E., Mussell, Ashley L., Shen, He, Truskinovsky, Alexander, Yang, Nuo, Parashurama, Natesh, Chen, Yanmin, Frangou, Costa, Yang, Fajun, Zhang, Jianmin
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2018
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5915420/
https://ncbi.nlm.nih.gov/pubmed/29691438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-24712-5
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