Whole exome sequencing identifies mTOR and KEAP1 as potential targets for radiosensitization of HNSCC cells refractory to EGFR and β1 integrin inhibition

Intrinsic and acquired resistances are major obstacles in cancer therapy. Genetic characterization is commonly used to identify predictive or prognostic biomarker signatures and potential cancer targets in samples from therapy-naïve patients. By far less common are such investigations to identify sp...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Oncotarget
Egile Nagusiak: Klapproth, Erik, Dickreuter, Ellen, Zakrzewski, Falk, Seifert, Michael, Petzold, Andreas, Dahl, Andreas, Schröck, Evelin, Klink, Barbara, Cordes, Nils
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Impact Journals LLC 2018
Gaiak:
Research Paper
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5915060/
https://ncbi.nlm.nih.gov/pubmed/29719593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.24266
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