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Hypothalamic GRP78, a new target against obesity?

The chaperone GRP78 (glucose related protein 78), also called BiP (binding immunoglobulin protein) is a key regulator of endoplasmic reticulum (ER) stress. We recently described that over-expression of GRP78 specifically in the ventromedial nucleus of the hypothalamus (VMH) releases hypothalamic ER...

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Publicat a:Adipocyte
Autors principals: Contreras, Cristina, Fondevila, Marcos F., López, Miguel
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5915027/
https://ncbi.nlm.nih.gov/pubmed/29261404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21623945.2017.1405878
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