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Single cell resolution of human hemato-endothelial cells defines transcriptional signatures of hemogenic endothelium

Endothelial-to-hematopoietic transition (EHT) is an important stage in definitive hematopoietic development. However, the genetic mechanisms underlying human EHT remains poorly characterized. We performed single cell RNA-seq using 55 hemogenic endothelial cells (HE: CD31(+)CD144(+)CD41(−)CD43(−)CD45...

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Bibliografische gegevens
Gepubliceerd in:Stem Cells
Hoofdauteurs: Angelos, Mathew G., Abrahante, Juan E., Blum, Robert H., Kaufman, Dan S.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2017
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5914515/
https://ncbi.nlm.nih.gov/pubmed/29139170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.2739
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