Nalaganje...
Targeting Ligandable Pockets on Plant Homeodomain (PHD) Zinc Finger Domains by a Fragment-Based Approach
[Image: see text] Plant homeodomain (PHD) zinc fingers are histone reader domains that are often associated with human diseases. Despite this, they constitute a poorly targeted class of readers, suggesting low ligandability. Here, we describe a successful fragment-based campaign targeting PHD finger...
Shranjeno v:
| izdano v: | ACS Chem Biol |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Chemical
Society
2018
|
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5913730/ https://ncbi.nlm.nih.gov/pubmed/29529862 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.7b01093 |
| Oznake: |
Označite
Brez oznak, prvi označite!
|