Differential protein expression and post-translational modifications in metronidazole-resistant Giardia duodenalis

BACKGROUND: Metronidazole (Mtz) is the frontline drug treatment for multiple anaerobic pathogens, including the gastrointestinal protist, Giardia duodenalis. However, treatment failure is common and linked to in vivo drug resistance. In Giardia, in vitro drug-resistant lines allow controlled experim...

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Detalhes bibliográficos
Publicado no:Gigascience
Main Authors: Emery, Samantha J, Baker, Louise, Ansell, Brendan R E, Mirzaei, Mehdi, Haynes, Paul A, McConville, Malcom J, Svärd, Staffan G, Jex, Aaron R
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5913674/
https://ncbi.nlm.nih.gov/pubmed/29688452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gigascience/giy024
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