Differential protein expression and post-translational modifications in metronidazole-resistant Giardia duodenalis

BACKGROUND: Metronidazole (Mtz) is the frontline drug treatment for multiple anaerobic pathogens, including the gastrointestinal protist, Giardia duodenalis. However, treatment failure is common and linked to in vivo drug resistance. In Giardia, in vitro drug-resistant lines allow controlled experim...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Gigascience
Hauptverfasser: Emery, Samantha J, Baker, Louise, Ansell, Brendan R E, Mirzaei, Mehdi, Haynes, Paul A, McConville, Malcom J, Svärd, Staffan G, Jex, Aaron R
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2018
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5913674/
https://ncbi.nlm.nih.gov/pubmed/29688452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gigascience/giy024
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