Immunization of Malaria-Preexposed Volunteers With PfSPZ Vaccine Elicits Long-Lived IgM Invasion-Inhibitory and Complement-Fixing Antibodies

BACKGROUND: The assessment of antibody responses after immunization with radiation-attenuated, aseptic, purified, cryopreserved Plasmodium falciparum sporozoites (Sanaria PfSPZ Vaccine) has focused on IgG isotype antibodies. Here, we aimed to investigate if P. falciparum sporozoite binding and invas...

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Detalhes bibliográficos
Publicado no:J Infect Dis
Main Authors: Zenklusen, Isabelle, Jongo, Said, Abdulla, Salim, Ramadhani, Kamaka, Lee Sim, B Kim, Cardamone, Hayley, Flannery, Erika L, Nguyen, Thao, Fishbaugher, Matthew, Steel, Ryan W J, Betz, Will, Carmago, Nelly, Mikolajczak, Sebastian, Kappe, Stefan H I, Hoffman, Stephen L, Sack, Brandon K, Daubenberger, Claudia
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Major Articles and Brief Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5913598/
https://ncbi.nlm.nih.gov/pubmed/29438525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiy080
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