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An evaluation of the operational model when applied to quantify functional selectivity
BACKGROUND AND PURPOSE: Functional selectivity describes the ability of ligands to differentially regulate multiple signalling pathways when coupled to a single receptor, and the operational model is commonly used to analyse these data. Here, we assess the mathematical properties of the operational...
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| Veröffentlicht in: | Br J Pharmacol |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
John Wiley and Sons Inc.
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5913411/ https://ncbi.nlm.nih.gov/pubmed/29457969 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14171 |
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