The GPSM2/LGN GoLoco motifs are essential for hearing

The planar cell polarity (PCP) pathway is responsible for polarizing and orienting cochlear hair cells during development through movement of a primary cilium, the kinocilium. GPSM2/LGN, a mitotic spindle-orienting protein associated with deafness in humans, is a PCP effector involved in kinocilium...

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Publicat a:Mamm Genome
Autors principals: Bhonker, Yoni, Abu-Rayyan, Amal, Ushakov, Kathy, Amir-Zilberstein, Liat, Shivatzki, Shaked, Yizhar-Barnea, Ofer, Elkan-Miller, Tal, Tayeb-Fligelman, Einav, Kim, Sun Myoung, Landau, Meytal, Kanaan, Moien, Chen, Ping, Matsuzaki, Fumio, Sprinzak, David, Avraham, Karen B.
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5913375/
https://ncbi.nlm.nih.gov/pubmed/26662512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00335-015-9614-7
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